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Advocate for Large Dogs : Uses, Dosage, and Safety

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If your dog needs protection against fleas and internal worms in Egypt’s warm climate, Advocate spot-on is a monthly treatment trusted by vets for broad-spectrum parasite control. This guide explains what Advocate does, which size to choose for large dogs, how to apply it correctly, and when you might combine it with a tick treatment.

What is Advocate?

Advocate is a topical, monthly spot-on for dogs containing imidacloprid and moxidectin. It:

  • Kills adult fleas and treats flea infestations
  • Treats ear mites and sarcoptic mange; aids in controlling demodicosis
  • Treats and controls roundworms and hookworms
  • Prevents heartworm disease with regular monthly use

Important note: Advocate does not kill ticks. If your dog needs tick protection, pair Advocate with a tick product (for example, a fluralaner chew) as advised by your vet.

Why choose Advocate for large dogs?

  • Broad-spectrum coverage in one monthly dose
  • Fast flea knockdown and ongoing protection
  • Heartworm prevention suited to endemic areas
  • Safe for regular year-round use when used as directed
  • Water-resistant once dry

Sizes and dosage for large dogs

advocate for large dogs
advocate for large dogs

Choose the correct pipette based on your dog’s weight.

Dog weightPack nameActives (approx.)Typical use
10–25 kgAdvocate for Large DogsImidacloprid 250 mg + Moxidectin 62.5 mgMonthly spot-on
25–40 kgAdvocate for Extra Large DogsImidacloprid 400 mg + Moxidectin 100 mgMonthly spot-on

If your dog is over 40 kg, your vet may advise a combination of pipettes to match body weight.

What Advocate treats

  • Fleas (adults) and flea allergy dermatitis support
  • Ear mites
  • Sarcoptic mange
  • Demodex control (as part of a vet-directed plan)
  • Roundworms and hookworms
  • Heartworm prevention with monthly, continuous use

Not covered: tapeworms and ticks. For tapeworms, a praziquantel dewormer is used separately. For ticks, add a tick-specific product.

How Advocate works

  • Imidacloprid targets fleas on contact
  • Moxidectin is absorbed transdermally to act against certain internal and external parasites, including heartworm larvae and intestinal nematodes

How to apply Advocate (step by step)

  • Check the dog’s bodyweight and select the correct pipette.
  • Part the hair at the base of the neck between the shoulder blades until skin is visible.
  • Place the tip on the skin and empty the entire contents directly on the skin. For very large dogs, you can divide the dose between 2–3 spots along the neck/upper back.
  • Apply to dry skin. Do not bathe the dog 48 hours before or after application.
  • Wash hands after use and prevent other pets from grooming the site until dry.
how to use spot on ampoules on pets
how to use spot on ampoules on pets

When to use and how often

  • Start from 7 weeks of age and at least 1 kg bodyweight (follow pack guidance and vet advice).
  • Apply monthly, all year round in Egypt to maintain continuous protection.
  • For dogs with known flea allergy dermatitis or in multi-pet homes, keep strict monthly intervals.

Safety and precautions

  • For dogs only; do not use the dog product on cats.
  • Generally well tolerated. Mild, temporary itching, hair clumping, or redness can occur at the application site.
  • Safe for use in pregnant and lactating bitches as directed.
  • Use with care in debilitated or underweight dogs. Consult your vet if your dog is on other macrocyclic lactones or is an MDR1-sensitive breed.
  • Avoid allowing the product to contact eyes or mouth. Store out of reach of children.

Advocate vs tick treatments (do you need both?)

If your dog hikes, visits farms, or lives in tick-prone areas, Advocate alone is not enough because it does not kill ticks. Many owners pair Advocate with a dedicated tick product. Compare your options below.

FeatureAdvocate (Imidacloprid + Moxidectin)Bravecto (Fluralaner)Simparica Trio (Sarolaner + Moxidectin + Pyrantel)
FleasYesYesYes
TicksNoYesYes
Heartworm preventionYesNoYes
Intestinal wormsRoundworms, HookwormsNoRoundworms, Hookworms
FormTopicalChewableChewable
DosingMonthly12-week (most markets)Monthly
Buy nowbuy advocate now.buy bravecto now.buy simparica trio now.

Tip: If you need both heartworm prevention and tick control, pair Advocate with a tick product, or discuss an all-in-one chew alternative with your vet.

Frequently asked questions

  • Does Advocate kill ticks? No. It covers fleas and multiple worms but not ticks.
  • How often should I apply it? Once every month, year-round.
  • Can I use Advocate if my dog swims? Yes, once dry. Avoid bathing or swimming for 48 hours after application.
  • Is Advocate safe during pregnancy and lactation? Yes, it can be used as directed. Consult your vet for an individualized plan.
  • Do I still need a tapeworm treatment? Yes, if tapeworm risk exists (e.g., hunting, raw diets, flea ingestion). Use a praziquantel-containing dewormer as advised.
  • My dog is 28 kg. Which size should I buy? Use Advocate for Extra Large Dogs (25–40 kg). Always dose to body weight.

Why shop at MyPetNeeds.me (Egypt)

advocate for large dogs
advocate for large dogs
  • Genuine, vet-trusted parasite control products
  • Fresh stock with proper Egyptian storage conditions
  • Fast Cairo and Alexandria delivery; nationwide shipping
  • Arabic and English support from pet care experts
  • Cash on delivery and local payment options

Elements for this page

  • Focus keyword: Advocate for large dogs
  • Secondary keywords: Advocate 10–25 kg, Advocate 25–40 kg, imidacloprid moxidectin dogs, flea and worm treatment for dogs, heartworm prevention Egypt, dog dewormer Egypt
  • Meta title: Advocate for Large Dogs (10–25 kg, 25–40 kg) | Flea, Worm & Heartworm Protection | MyPetNeeds.me
  • Meta description: Protect your large dog with Advocate spot-on. Monthly flea control, roundworm and hookworm treatment, and heartworm prevention. Fast delivery across Egypt from MyPetNeeds.me

Quick buying checklist

  • Weigh your dog and choose the correct size (10–25 kg or 25–40 kg)
  • Apply monthly on dry skin
  • Add a tick product if needed
  • Keep consistent year-round protection in Egypt
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